Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Association of CTLA-4 gene microsatellite polymorphism with ulcerative colitis in Chinese patients.

Inflammatory bowel diseases - 1 May 2006

Jiang Yi, Xia Bing, Jiang Li, Lv Min, Guo Qiusha, Chen Min, Li Jin, Xia Harry Hua-Xiang, Wong Benjamin Chun-Yu

Abstract excerpt

Ulcerative colitis (UC) is characterized by chronic intestinal inflammation as a result of an exaggerated T cell response. Cytotoxic T lymphocyte associated antigen-4 (CTLA-4), expressed mainly in activated T cells, inhibits T cell activation and proliferation by combining B7 through competing CD28 and maintains immune homeostasis. Polymorphisms of the CTLA-4 gene are known to be associated with several...

Topics

Join the communities discussing this publication.

Antigens, CD
Antigens, Differentiation
Asian People
China
Colitis, Ulcerative

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Microsatellite Repeats

Polymorphism, Genetic

Source

Identifiers

PMID: 16670525
DOI: 10.1097/01.MIB.0000217339.61183.dd

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of CTLA-4 gene microsatellite polymorphism with ulcerative colitis in Chinese patients.PMID 16670525Read ↗

CTLA-4 gene polymorphisms in Chinese patients with ulcerative colitis.Semantic proximity Read ↗

CTLA4 -1661A/G and 3'UTR long repeat polymorphisms are associated with ulcerative colitis and influence CTLA4 mRNA and protein expression.Semantic proximity Read ↗

Association of polymorphic alleles of CTLA4 with inflammatory bowel disease in the Japanese.Semantic proximity Read ↗

Cytotoxic T lymphocyte antigen-4 promoter -658CT gene polymorphism is associated with ulcerative colitis in Chinese patients.Semantic proximity Read ↗

CTLA-4 polymorphisms and susceptibility to inflammatory bowel disease: a meta-analysis.Semantic proximity Read ↗

Analysis of cytotoxic T lymphocyte associated antigen 4 gene polymorphisms in patients with ulcerative colitis.Semantic proximity Read ↗

[CTLA-4 gene polymorphism regulates CTLA-4 mRNA stability and protein level in patients with ulcerative colitis].Semantic proximity Read ↗

[Association of cytotoxic T lymphocyte antigen-4 promoter C-658T polymorphism with ulcerative colitis in Chinese].Semantic proximity Read ↗

CTLA4 gene polymorphisms in Dutch and Chinese patients with inflammatory bowel disease.Semantic proximity Read ↗

[Cytotoxic T lymphocyte antigen-4 promoter gene polymorphism is significantly associated with ulcerative colitis].Semantic proximity Read ↗

Association of CTLA-4 variants with susceptibility to inflammatory bowel disease: a meta-analysis.Semantic proximity Read ↗

Genetic polymorphisms of interleukin 8 and risk of ulcerative colitis in the Chinese population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.