Article
CTLA-4 polymorphisms and susceptibility to inflammatory bowel disease: a meta-analysis.
Human immunology - 1 May 2014
Lee Young Ho, Kim Jae-Hoon, Seo Young Ho, Choi Sung Jae, Ji Jong Dae, Song Gwan Gyu
Abstract excerpt
OBJECTIVE: The aim of this study was to explore whether the cytotoxic T lymphocyte associated antigen-4 (CTLA-4) polymorphisms are associated with susceptibility to ulcerative colitis (UC) and Crohn's disease (CD). METHODS: The authors conducted a meta-analysis on associations between CTLA-4 +49 A/G, -318 C/T, CT60 A/G polymorphisms, and (AT)n repeat in the 3' untranslated region (UTR) and UC and CD...
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