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Cytotoxic T lymphocyte antigen-4 promoter -658CT gene polymorphism is associated with ulcerative colitis in Chinese patients.

International journal of colorectal disease - 1 May 2009

Luo Yan, Xia Bing, Li Chun, Chen Zhitao, Ge Liuqing, Jiang Ting, Zhou Feng, Zhao Yan

Abstract excerpt

BACKGROUND AND AIM: Cytotoxic T lymphocyte antigen-4 (CTLA-4) plays a role in the downregulation of T cell activation. The present study aimed to examine an association between the CTLA-4 gene polymorphisms and ulcerative colitis (UC) in the Han Chinese in central China. MATERIALS AND METHODS: One hundred seventeen patients with UC and 246 healthy controls were genotyped for CTLA-4 gene -658CT in the promoter and...

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Aged, 80 and over
Antigens, CD
Asian People
China
Colitis, Ulcerative

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single-Stranded Conformational

Promoter Regions, Genetic

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PMID: 19089435
DOI: 10.1007/s00384-008-0626-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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