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Article

Association between the cytotoxic T-lymphocyte antigen 4 +49A/G polymorphism and bladder cancer risk.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Feb 2014

Wang Lei, Su Guixiang, Zhao Xinghua, Cai Yi, Cai Xianan, Zhang Jie, Liu Jian, Wang Tongqing, Wang Jizheng

Abstract excerpt

Cytotoxic T-lymphocyte antigen 4 (CTLA-4) is a potent immunoregulatory molecule that suppresses antitumor response by downregulating T cell activation. The most studied CTLA-4 +49A/G polymorphism has been associated with various cancers risks. However, little is known about the association between CTLA-4 +49A/G polymorphism and bladder cancer risk. A hospital-based case-control study was conducted in 300 patients...

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Identifiers

PMID: 24014088
DOI: 10.1007/s13277-013-1152-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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