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Analysis of cytotoxic T lymphocyte associated antigen 4 gene polymorphisms in patients with ulcerative colitis.

Journal of gastroenterology and hepatology - 1 Feb 2006

Lankarani Kamran B, Karbasi Ashraf, Kalantari Tahereh, Yarmohammadi Hooman, Saberi-Firoozi Mehdi, Alizadeh-Naeeni Mahvash, Taghavi Ali R, Fattahi Mahammad R, Ghaderi Abbas

Abstract excerpt

BACKGROUND AND AIM: Ulcerative colitis (UC) is a multifactorial disease associated with dysregulated immunity. Recently, cytotoxic T lymphocyte associated antigen 4 (CTLA-4) gene polymorphisms have been reported in association with several autoimmune diseases in several populations. In the present study, the possible implication of the CTLA-4 gene as a risk factor for UC in the Iranian population was...

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Antigens, CD
Antigens, Differentiation
Colitis, Ulcerative
CTLA-4 Antigen
DNA

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PMID: 16509873
DOI: 10.1111/j.1440-1746.2005.03956.x

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