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Article

T-cell regulatory gene CTLA-4 polymorphism/haplotype association with autoimmune pancreatitis.

Clinical chemistry - 1 Sept 2007

Chang Ming-Chu, Chang Yu-Ting, Tien Yu-Wen, Liang Po-Chin, Jan I-Shiow, Wei Shu-Chen, Wong Jau-Min

Abstract excerpt

BACKGROUND: Autoimmune pancreatitis (AIP) is a distinct disease entity of chronic pancreatitis. Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) is a key negative regulator of the T-cell immune response, and its gene is highly polymorphic. Many positive associations between cytotoxic T-lymphocyte-associated protein 4 (CTLA4) single-nucleotide polymorphisms and various autoimmune diseases have been identified....

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Source

Identifiers

PMID: 17712006
DOI: 10.1373/clinchem.2007.085951

Genes

AIP
CTLA4
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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