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Article

Genetics of psoriasis in Iceland: evidence for linkage of subphenotypes to distinct Loci.

The Journal of investigative dermatology - 1 Jun 2005

Karason Ari, Gudjonsson Johann E, Jónsson Hjörtur H, Hauksson Valdimar B, Runarsdottir E Hjaltey, Stefansson Kari, Valdimarsson Helgi, Gulcher Jeffrey R

Abstract excerpt

Psoriasis is a chronic inflammatory skin disease with overlapping subphenotypes. It has a strong complex genetic component, but has been problematic to identifying significant loci. We evaluated 1000 patients with chronic plaque psoriasis and documented several subphenotypes. Here we report results of genome-wide linkage scans for psoriasis genes in 238 Icelandic families with 874 patients. MHC linkage was...

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Identifiers

PMID: 15955092
DOI: 10.1111/j.0022-202X.2005.23703.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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