Article
Linkage of essential hypertension to chromosome 18q.
Hypertension (Dallas, Tex. : 1979) - 1 Jun 2002
Kristjansson Kristleifur, Manolescu Andrei, Kristinsson Arni, Hardarson Thordur, Knudsen Helga, Ingason Sigurdur, Thorleifsson Gudmar, Frigge Michael L, Kong Augustine, Gulcher Jeffrey R, Stefansson Kari
Abstract excerpt
We performed a genomewide scan with 904 microsatellite markers using 120 extended Icelandic families with 490 hypertensive patients. The families were identified by cross-matching a list of hypertensive patients from the Hypertension Clinic of the University Hospital (Landspitalinn) in Iceland with a genealogy database of the entire Icelandic nation. After adding 5 markers, we found linkage to chromosome 18q with...
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