Article
Analysis of three suggested psoriasis susceptibility loci in a large Swedish set of families: confirmation of linkage to chromosome 6p (HLA region), and to 17q, but not to 4q.
Human heredity - 1 Jan 1999
Enlund F, Samuelsson L, Enerbäck C, Inerot A, Wahlström J, Yhr M, Torinsson A, Martinsson T, Swanbeck G
Abstract excerpt
Psoriasis is known to be a heterogeneous disease with so far three reported major psoriasis susceptibility loci on chromosome 4q, 6p and 17q. In this study we investigated three reported gene locations by nonparametric and parametric linkage analysis in a large family set consisting of 104 famili...
Topics
- Chromosomes, Human, Pair 17
- Chromosomes, Human, Pair 4
- Chromosomes, Human, Pair 6
- Family Health
- Genetic Linkage
- Genetic Predisposition to Disease
- HLA Antigens
- Humans
- Linkage Disequilibrium
- Lod Score
- Psoriasis
- Sweden