Article
Characterization of a susceptibility locus for SLE, SLEB5, on chromosome 4p14-13.
Scandinavian journal of immunology - 1 Sept 2006
Johansson C M, Kristjánsdottir H, Gröndal G, Steinsson K, Alarcón-Riquelme M E
Abstract excerpt
Systemic lupus erythematosus is a systemic autoimmune disorder of unknown aetiology but is most likely caused by an interaction between several genetic factors and the environment. In a previously published genome scan we presented linkage to a marker on chromosome 4p13 in Icelandic families. Fine mapping of the region has been performed using 10 multicase families from Iceland and the maximum two-point LOD score...
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