Article
Variants in linkage disequilibrium with the late cornified envelope gene cluster deletion are associated with susceptibility to psoriatic arthritis.
Annals of the rheumatic diseases - 1 Dec 2010
Bowes John, Flynn Edward, Ho Pauline, Aly Batool, Morgan Ann W, Marzo-Ortega Helena, Coates Laura, McManus Ross, Ryan Anthony W, Kane David, Korendowych Eleanor, McHugh Neil, FitzGerald Oliver, Packham Jonathan, Bruce Ian N, Barton Anne
Abstract excerpt
OBJECTIVE: A common deletion mapping to the psoriasis susceptibility locus 4 on chromosome 1q21, encompassing two genes of the late cornified envelope (LCE) gene cluster, has been associated with an increased risk of psoriasis vulgaris (PsV). One previous report found no association of the deleti...
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