Article
A genome-wide search for genes predisposing to familial psoriasis by using a stratification approach.
Human genetics - 1 Dec 1999
Samuelsson L, Enlund F, Torinsson A, Yhr M, Inerot A, Enerbäck C, Wahlström J, Swanbeck G, Martinsson T
Abstract excerpt
We have performed a genome scan, using markers spaced by 10 cM, in the search for psoriasis-susceptibility loci. The family material of 134 affected sibling pairs was ascertained on the basis of a population genetic study in which 65% of the probands had two healthy parents. Genotyping results were analyzed for non-random excessive allele-sharing between sib pairs by using GENEHUNTER ver 1.1. A stratification...
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