Article
A susceptibility gene for psoriatic arthritis maps to chromosome 16q: evidence for imprinting.
American journal of human genetics - 1 Jan 2003
Karason Ari, Gudjonsson Johann E, Upmanyu Ruchi, Antonsdottir Arna A, Hauksson Valdimar B, Runasdottir E Hjaltey, Jonsson Hjortur H, Gudbjartsson Daniel F, Frigge Michael L, Kong Augustine, Stefansson Kari, Valdimarsson Helgi, Gulcher Jeffrey R
Abstract excerpt
Several genetic loci have been reported for psoriasis, but none has been specifically linked to psoriatic arthritis (PsA), a condition that affects >10% of patients with psoriasis. A genetic component for PsA is suggested by segregation within families and high concordance among identical twins. We performed a linkage scan to map genes contributing to PsA. We identified 178 patients with PsA out of 906 patients...
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