Article
Linkage of atopic dermatitis to chromosomes 4q22, 3p24 and 3q21.
Human genetics - 1 Oct 2009
Christensen Ulla, Møller-Larsen Steffen, Nyegaard Mette, Haagerup Annette, Hedemand Anne, Brasch-Andersen Charlotte, Kruse Torben A, Corydon Thomas Juhl, Deleuran Mette, Børglum Anders D
Abstract excerpt
Atopic dermatitis (AD) is a common, itchy skin disease of complex inheritance characterized by dermal and epidermal inflammation. The heritability is considerable and well documented. To date, four genome scans have examined the AD phenotype, showing replicated linkage at 3p26-22, 3q13-21 and 18q11-21. Our previous AD scan showed evidence of linkage to loci at 3p and 18q, and furthermore at 4p15-14. In order to...
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