Gene for familial psoriasis susceptibility mapped to the distal end of human chromosome 17q.

doi:10.1126/science.8178173

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Article

Gene for familial psoriasis susceptibility mapped to the distal end of human chromosome 17q.

Science (New York, N.Y.) - 20 May 1994

Tomfohrde J, Silverman A, Barnes R, Fernandez-Vina M A, Young M, Lory D, Morris L, Wuepper K D, Stastny P, Menter A

Abstract excerpt

A gene involved in psoriasis susceptibility was localized to the distal region of human chromosome 17q as a result of a genome-wide linkage analysis with polymorphic microsatellites and eight multiply affected psoriasis kindreds. In the family which showed the strongest evidence for linkage, the...

Topics

Alleles
Base Sequence
Chromosome Mapping
Chromosomes, Human, Pair 17
DNA Primers
DNA, Satellite
Disease Susceptibility
Female
Genetic Linkage
Genetic Markers
HLA-C Antigens
Haplotypes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Lod Score

Male

Molecular Sequence Data

Pedigree

Polymorphism, Genetic

Source

Open in PubMed

Identifiers

PMID: 8178173
DOI: 10.1126/science.8178173

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8178173-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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