Article
Genetic linkage of childhood atopic dermatitis to psoriasis susceptibility loci.
Nature genetics - 1 Apr 2001
Cookson W O, Ubhi B, Lawrence R, Abecasis G R, Walley A J, Cox H E, Coleman R, Leaves N I, Trembath R C, Moffatt M F, Harper J I
Abstract excerpt
We have carried out a genome screen for atopic dermatitis (AD) and have identified linkage to AD on chromosomes 1q21, 17q25 and 20p. These regions correspond closely with known psoriasis loci, as does a previously identified AD locus on chromosome 3q21. The results indicate that AD is influenced by genes with general effects on dermal inflammation and immunity.
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