Article
Aberrantly glycosylated serum IgA1 are closely associated with pathologic phenotypes of IgA nephropathy.
Kidney international - 1 Jul 2005
Xu Li-Xia, Zhao Ming-Hui
Abstract excerpt
BACKGROUND: IgA nephropathy (IgAN) is the most common glomerulonephritis with various histologic and clinical phenotypes. The mechanisms underlying the pathogenesis of IgAN remained unclear. But now altered O-glycosylation of serum IgA1 observed in these patients was considered to be a key contributory factor. The aim of the current study is to investigate whether aberrantly glycosylated IgA1 was associated with...
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