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Article

Cellular signaling and production of galactose-deficient IgA1 in IgA nephropathy, an autoimmune disease.

Journal of immunology research - 1 Jan 2014

Reily Colin, Ueda Hiroyuki, Huang Zhi-Qiang, Mestecky Jiri, Julian Bruce A, Willey Christopher D, Novak Jan

Abstract excerpt

Immunoglobulin A (IgA) nephropathy (IgAN), the leading cause of primary glomerulonephritis, is characterized by IgA1-containing immunodeposits in the glomeruli. IgAN is a chronic disease, with up to 40% of patients progressing to end-stage renal disease, with no disease-specific treatment. Multiple studies of the origin of the glomerular immunodeposits have linked elevated circulating levels of aberrantly...

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Share to Glomerulonephritis, IGA
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25152896
DOI: 10.1155/2014/197548
PMCID: PMC4134797

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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