Article
The glycans deficiencies of macromolecular IgA1 is a contributory factor of variable pathological phenotypes of IgA nephropathy.
Clinical and experimental immunology - 1 Dec 2005
Xu L-X, Yan Y, Zhang J-J, Zhang Y, Zhao M-H
Abstract excerpt
Recent evidence has suggested that IgA1-containing macromolecules and the glycosylation of IgA1 in sera from patients with IgAN might involve the pathogenesis of IgAN. However, whether the different histological phenotypes can be attributed or not to the aberrant glycosylation of macromolecular IgA1 has not yet been elucidated. The aim of the current study is to investigate the glycosylation of IgA1 molecules in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
