Article
Self-aggregated deglycosylated IgA1 with or without IgG were associated with the development of IgA nephropathy.
Clinical and experimental immunology - 1 Apr 2006
Yan Y, Xu L-X, Zhang J-J, Zhang Y, Zhao M-H
Abstract excerpt
IgA nephropathy (IgAN) is the most common primary glomerulonephritis, with various pathological phenotypes. Our previous study suggested that aberrant glycosylation of serum IgA1 was associated with different pathological phenotypes of IgAN, and substantial evidence indicated that deglycosylated IgA1 had an increased tendency to form macromolecules. The aim of the current study was to investigate the composition...
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