Article
RNA interference is ineffective as a routine method for gene silencing in chick embryos as monitored by fgf8 silencing.
International journal of biological sciences - 1 Jan 2005
Hernández Victor Hernández, Bueno David
Abstract excerpt
The in vivo accessibility of the chick embryo makes it a favoured model system for experimental developmental biology. Although the range of available techniques now extends to miss-expression of genes through in ovo electroporation, it remains difficult to knock out individual gene expression. Recently, the possibility of silencing gene expression by RNAi in chick embryos has been reported. However, published...
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