Article
RNAi-based gene silencing in chicken brain development.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2014
Andermatt Irwin, Stoeckli Esther T
Abstract excerpt
The mouse is the most commonly used vertebrate model for the analysis of gene function because of the well-established genetic tools that are available for loss-of-function studies. However, studies of gene function during development can be problematic in mammals. Many genes are active during different stages of development. Absence of gene function during early development may cause embryonic lethality and thus...
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