Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Double-stranded RNA induces specific developmental defects in zebrafish embryos.

Biochemical and biophysical research communications - 16 Sept 1999

Wargelius A, Ellingsen S, Fjose A

Abstract excerpt

Treatment with double-stranded RNA (dsRNA) has been shown to interfere with the function of specific genes in various invertebrate species. However, it has not yet been reported that this technique can be applied to vertebrates as well. We have investigated whether dsRNA treatment will inhibit gene function in zebrafish embryos. By microinjecting dsRNA corresponding to three genetically characterised genes we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to DNA Primers
Share to Gene Expression Regulation, Developmental

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Microinjections

Share to Phenotype

Share to RNA, Double-Stranded

Share to RNA, Messenger

Share to Zebrafish

Source

Identifiers

PMID: 10486270
DOI: 10.1006/bbrc.1999.1343

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Double-stranded RNA induces specific developmental defects in zebrafish embryos.PMID 10486270Read ↗

Double-stranded RNA injection produces null phenotypes in zebrafish.Semantic proximity Read ↗

Efficient RNA interference in zebrafish embryos using siRNA synthesized with SP6 RNA polymerase.Semantic proximity Read ↗

Using zinc finger nucleases for efficient and heritable gene disruption in zebrafish.Semantic proximity Read ↗

New tools for gene manipulation in chicken embryos.Semantic proximity Read ↗

Generating Stable Knockout Zebrafish Lines by Deleting Large Chromosomal Fragments Using Multiple gRNAs.Semantic proximity Read ↗

RNA interference by feeding in vitro-synthesized double-stranded RNA to planarians: methodology and dynamics.Semantic proximity Read ↗

Large scale genetics in a small vertebrate, the zebrafish.Semantic proximity Read ↗

Reverse Genetics in Zebrafish: Mutants, Morphants, and Moving Forward.Semantic proximity Read ↗

Reverse genetic screening reveals poor correlation between morpholino-induced and mutant phenotypes in zebrafish.Semantic proximity Read ↗

Use of dsRNA-mediated genetic interference to demonstrate that frizzled and frizzled 2 act in the wingless pathway.Semantic proximity Read ↗

Developmental mutant screens in the zebrafish.Semantic proximity Read ↗

Out with the old, in with the new: reassessing morpholino knockdowns in light of genome editing technology.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.