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Article

Estimating haplotype frequencies in pooled DNA samples when there is genotyping error.

BMC genetics - 19 May 2005

Quade Shannon R E, Elston Robert C, Goddard Katrina A B

Abstract excerpt

BACKGROUND: Maximum likelihood estimates of haplotype frequencies can be obtained from pooled DNA using the expectation maximization (EM) algorithm. Through simulation, we investigate the effect of genotyping error on the accuracy of haplotype frequency estimates obtained using this algorithm. We explore model parameters including allele frequency, inter-marker linkage disequilibrium (LD), genotyping error rate,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 15943883
DOI: 10.1186/1471-2156-6-25
PMCID: PMC1156884

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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