Haplotype inference for population data with genotyping errors.

Abstract excerpt

Inference of haplotypes is important in genetic epidemiology studies. However, all large genotype data sets have errors due to the use of inexpensive genotyping machines that are fallible and shortcomings in genotyping scoring softwares, which can have an enormous impact on haplotype inference. In this article, we propose two novel strategies to reduce the impact induced by genotyping errors in haplotype...

Topics

• Algorithms
• Animals
• Computer Simulation
• Data Interpretation, Statistical
• Genetics, Population
• Haplotypes
• Humans
• Models, Genetic
• Models, Statistical
• Polymorphism, Single Nucleotide