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Article

PoooL: an efficient method for estimating haplotype frequencies from large DNA pools.

Bioinformatics (Oxford, England) - 1 Sept 2008

Zhang Han, Yang Hsin-Chou, Yang Yaning

Abstract excerpt

MOTIVATION: Pooling DNA is a cost-effective alternative to individual genotyping method. It is often used for initial screening in genome-wide association analysis. In some studies, large pools with sizes up to several hundreds were applied in order to significantly reduce genotyping cost. However, method for estimating haplotype frequencies from large DNA pools has not been available due to computational...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18573795
DOI: 10.1093/bioinformatics/btn324

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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