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Article

Lower core body temperature and attenuated nicotine-induced hypothermic response in mice lacking the beta4 neuronal nicotinic acetylcholine receptor subunit.

Brain research bulletin - 15 Jul 2005

Sack Ram, Gochberg-Sarver Alona, Rozovsky Uri, Kedmi Merav, Rosner Serena, Orr-Urtreger Avi

Abstract excerpt

Diverse physiological and pathological effects of nicotine, including the alteration of body temperature, are presumably mediated by neuronal nicotinic acetylcholine receptors (nAChR). Previous studies have suggested the involvement of distinct nAChR subunits in nicotine-induced thermoregulation. We studied genetically manipulated knockout mice lacking the alpha7, alpha5 or beta4 subunit genes, in order to assess...

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Identifiers

PMID: 15925141
DOI: 10.1016/j.brainresbull.2005.02.032

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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