Article
Neuronal nicotinic receptors: insights gained from gene knockout and knockin mutant mice.
Cellular and molecular life sciences : CMLS - 1 Jul 2003
Drago J, McColl C D, Horne M K, Finkelstein D I, Ross S A
Abstract excerpt
Neuronal nicotinic acetylcholine receptors are ligand-gated ion channels that subserve a range of functions in the brain and peripheral nervous system. They are pentamers variously composed of alpha (alpha2-alpha10) and beta subunits (beta2-beta4). Pharmacological and ligand-binding studies have shown that the different subunits vary in their distribution and channel properties, but precise delineation of the in...
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