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Article

Tolerance to nicotine in mice lacking alpha7 nicotinic receptors.

Psychopharmacology - 1 Jul 2005

Naylor C, Quarta D, Fernandes C, Stolerman I P

Abstract excerpt

RATIONALE: Previous studies have suggested that a knockout of the gene coding for alpha7 nicotinic receptor subunits influences the behaviour of undrugged mice but not the acute effect of nicotine on locomotor activity. OBJECTIVES: The present studies extend these observations to nicotine tolerance assessed by means of schedule-controlled behaviour. METHODS: Groups of alpha7-/- and alpha7+/+ mice were trained to...

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Source

Identifiers

PMID: 15723228
DOI: 10.1007/s00213-005-2187-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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