Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prevention of type 1 diabetes with major histocompatibility complex-compatible and nonmarrow ablative hematopoietic stem cell transplants.

Diabetes - 1 Jun 2005

Beilhack Georg F, Landa Rosa R, Masek Marilyn A, Shizuru Judith A

Abstract excerpt

Progression to hyperglycemia in young nonobese diabetic (NOD) mice is blocked by the transplantation of hematopoietic cells mismatched at the major histocompatibility complex (MHC). Because the NOD MHC class II allele, I-A(g7), is the primary disease susceptibility gene, it is logical to conclude...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to B-Lymphocytes
Share to Diabetes Mellitus, Type 1
Share to Major Histocompatibility Complex

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Inbred NOD

Share to T-Lymphocyte Subsets

Share to Transplantation Chimera

Share to Transplantation Conditioning

Share to Transplantation, Homologous

Source

Identifiers

PMID: 15919799
DOI: 10.2337/diabetes.54.6.1770

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15919799-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prevention of type 1 diabetes with major histocompatibility complex-compatible and nonmarrow ablative hematopoietic stem cell transplants.PMID 15919799Read ↗

Prevention of type 1 diabetes by gene therapySemantic proximity Read ↗

Mixed allogeneic chimerism induced by a sublethal approach prevents autoimmune diabetes and reverses insulitis in nonobese diabetic (NOD) mice.Semantic proximity Read ↗

Induction of robust diabetes resistance and prevention of recurrent type 1 diabetes following islet transplantation by gene therapy.Semantic proximity Read ↗

Transgenic rescue implicates beta2-microglobulin as a diabetes susceptibility gene in nonobese diabetic (NOD) mice.Semantic proximity Read ↗

Bone marrow expressing a diabetes resistance MHC class II allele: diabetes deviation by chronic immune stimulation.Semantic proximity Read ↗

Transfusion of nonobese diabetic mice with allogeneic newborn blood ameliorates autoimmune diabetes and modifies the expression of selected immune response genes.Semantic proximity Read ↗

NOD congenic mice genetically protected from autoimmune diabetes remain resistant to transplantation tolerance induction.Semantic proximity Read ↗

Selective deletion of human leukocyte antigens protects stem cell-derived islets from immune rejection.Semantic proximity Read ↗

Human immune system development and rejection of human islet allografts in spontaneously diabetic NOD-Rag1null IL2rgammanull Ins2Akita mice.Semantic proximity Read ↗

Hematopoietic Stem Cells in Type 1 Diabetes.Semantic proximity Read ↗

Bridging mice to men: using HLA transgenic mice to enhance the future prediction and prevention of autoimmune type 1 diabetes in humans.Semantic proximity Read ↗

Reduction in diabetes incidence in an I-Ag7 transgenic nonobese diabetic mouse line.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.