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Article

Hematopoietic Stem Cells in Type 1 Diabetes.

Frontiers in immunology - 1 Jan 2021

Pastore Ida, Assi Emma, Ben Nasr Moufida, Bolla Andrea Mario, Maestroni Anna, Usuelli Vera, Loretelli Cristian, Seelam Andy Joe, Abdelsalam Ahmed, Zuccotti Gian Vincenzo, D'Addio Francesca, Fiorina Paolo

Abstract excerpt

Despite the increasing knowledge of pathophysiological mechanisms underlying the onset of type 1 diabetes (T1D), the quest for therapeutic options capable of delaying/reverting the diseases is still ongoing. Among all strategies currently tested in T1D, the use of hematopoietic stem cell (HSC)-based approaches and of teplizumab, showed the most encouraging results. Few clinical trials have already demonstrated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34305929
DOI: 10.3389/fimmu.2021.694118
PMCID: PMC8299361

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