Article
Transfusion of nonobese diabetic mice with allogeneic newborn blood ameliorates autoimmune diabetes and modifies the expression of selected immune response genes.
Journal of immunology (Baltimore, Md. : 1950) - 15 Mar 2010
Jayaraman Sundararajan, Patel Tejas, Patel Vasu, Ajani Shahnaz, Garza Rebecca, Jayaraman Arathi, Kwon Sung, Singh Rajvir, Rondelli Damiano, Prabhakar Bellur S, Holterman Mark
Abstract excerpt
Although allogeneic bone marrow transplantation has been shown to prevent autoimmune diabetes in heavily irradiated nonobese diabetic (NOD) mice, a similar procedure is not suitable for the treatment of patients with type 1 diabetes because of associated severe side effects. Therefore, we evaluat...
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