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Article

Somatic mutation of mitochondrial DNA in Helicobacter pylori-associated chronic gastritis in patients with and without gastric cancer.

International journal of molecular medicine - 1 Aug 2003

Hiyama Toru, Tanaka Shinji, Shima Hideyuki, Kose Kazuhiro, Kitadai Yasuhiko, Ito Masanori, Sumii Masaharu, Yoshihara Masaharu, Shimamoto Fumio, Haruma Ken, Chayama Kazuaki

Abstract excerpt

Somatic mutations of the mitochondrial DNA (mtDNA) are associated with development of various types of human cancer. To elucidate the significance of somatic mutations of the mtDNA in gastric carcinogenesis, we examined mtDNA mutations in gastric cancers and in Helicobacter pylori-associated chronic gastritis (H. pylori-CG), which is associated with an increased risk for gastric cancer development. Specimens of...

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PMID: 12851712

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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