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Article

IgV H mutations in blastoid mantle cell lymphoma characterize a subgroup with a tendency to more favourable clinical outcome.

The Journal of pathology - 1 Jul 2005

Cogliatti Sergio B, Bertoni Francesco, Zimmermann Dieter R, Henz Samuel, Diss Tim C, Ghielmini Michele, Schmid Ulrico

Abstract excerpt

Mantle cell lymphoma (MCL) is associated with a very unfavourable clinical course. This is particularly true for mantle cell lymphoma of the blastoid subtype (MCL-b). In order to define prognostic factors, we analysed the impact of immunoglobulin heavy chain variable (IgV H) gene somatic hypermutations on clinical outcome in a series of 21 cases of morphologically, phenotypically, and genotypically...

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Identifiers

PMID: 15887292
DOI: 10.1002/path.1781

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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