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Article

Burkitt's lymphomas express VH genes with a moderate number of antigen-selected somatic mutations.

The American journal of pathology - 1 Nov 1995

Tamaru J, Hummel M, Marafioti T, Kalvelage B, Leoncini L, Minacci C, Tosi P, Wright D, Stein H

Abstract excerpt

The normal counterpart of the neoplastic B cells occurring in Burkitt's lymphomas (BL) is an issue of controversial debate. To clarify this matter, a semi-nested primer polymerase chain reaction was performed to amplify the VDJ rearrangements of the immunoglobulin heavy chain (VH) gene of DNA extracts from 10 (8 sporadic and 2 endemic) BL cases. The resulting amplificates were sequenced for comparison with known...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 7485402
PMCID: PMC1869537

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Burkitt's lymphomas express VH genes with a moderate number of antigen-selected somatic mutations.PMID 7485402Read ↗

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