Article
CD10-positive mantle cell lymphoma: biologically distinct entity or an aberrant immunophenotype? Insight, through gene expression profile in a unique case series.
Journal of clinical pathology - 1 Oct 2015
Akhter Ariz, Mahe Etienne, Street Lesley, Pournazari Payam, Perizzolo Marco, Shabani-Rad Meer-Taher, Stewart Douglas A, Mansoor Adnan
Abstract excerpt
BACKGROUND: Mantle cell lymphoma (MCL) is an aggressive disease with genetic heterogeneity and discrete clinical subtypes. MCL is rarely CD10 positive. These cases raise the question whether a subset of MCL may be germinal centre (GC) derived, and have distinct clinicopathological characteristics. AIMS AND METHODS: A series of nine CD10-positive MCL cases is described herein. The clinicopathological and...
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