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Article

Blastic variant of mantle cell lymphoma shows a heterogenous pattern of somatic mutations of the rearranged immunoglobulin heavy chain variable genes.

British journal of haematology - 1 Sept 1998

Pittaluga S, Tierens A, Pinyol M, Campo E, Delabie J, De Wolf-Peeters C

Abstract excerpt

Mantle cell lymphoma is a distinct clinicopathological entity associated with t(11;14) and cyclin D1 overexpression. The majority of cases show uniform morphological and phenotypic features characterized by a monotonous proliferation of small-to-medium-sized irregular B cells that express CD5 and bright surface immunoglobulin IgM and IgD. By sequence analysis of the rearranged immunoglobulin heavy chain variable...

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Share to Gene Rearrangement, B-Lymphocyte, Heavy Chain

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9753060
DOI: 10.1046/j.1365-2141.1998.00907.x

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Source receipt: pubmed, retrieved 7 Sept 2026.

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