Blastic variant of mantle cell lymphoma shows a heterogenous pattern of somatic mutations of the rearranged immunoglobulin heavy chain variable genes.

doi:10.1046/j.1365-2141.1998.00907.x

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Article

Blastic variant of mantle cell lymphoma shows a heterogenous pattern of somatic mutations of the rearranged immunoglobulin heavy chain variable genes.

British journal of haematology - 1 Sept 1998

Pittaluga S, Tierens A, Pinyol M, Campo E, Delabie J, De Wolf-Peeters C

Abstract excerpt

Mantle cell lymphoma is a distinct clinicopathological entity associated with t(11;14) and cyclin D1 overexpression. The majority of cases show uniform morphological and phenotypic features characterized by a monotonous proliferation of small-to-medium-sized irregular B cells that express CD5 and...

Topics

Amino Acid Sequence
Gene Rearrangement, B-Lymphocyte, Heavy Chain
Humans
Lymphoma, Non-Hodgkin
Molecular Sequence Data
Mutation
Reverse Transcriptase Polymerase Chain Reaction
Sequence Analysis

Source

Open in PubMed

Identifiers

PMID: 9753060
DOI: 10.1046/j.1365-2141.1998.00907.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9753060-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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