Article
Arylamine N-acetyltransferase 2 expression in the developing heart.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society - 1 May 2005
Wakefield Larissa, Cornish Valerie, Broackes-Carter Fiona, Sim Edith
Abstract excerpt
Murine arylamine N-acetyltransferase 2 (NAT2) is expressed in the developing heart and in the neural tube at the time of closure. Classically described as a xenobiotic metabolizing enzyme, there is increasing evidence for a distinct biological role for murine NAT2. We have characterized the expression of arylamine N-acetyltransferase 2 during cardiogenesis, mapping its expression in vivo, using a lacZ insertion...
Topics
- Acetylation
- Amino Acid Transport System A
- Amino Acid Transport Systems
- Animals
- Animals, Newborn
- Female
- Genotype
- Heart
- Heart Atria
- Heart Valves
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Myocardium
- Pulmonary Artery
