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Structural Analysis of the Genes for Human Arylamine N-Acetyltransferases and Characterisation of Alternative Transcripts

26 Apr 2005

Abstract excerpt

Arylamine N-acetyltransferases are polymorphic drug-metabolising enzymes. The human isoforms, NAT1 and NAT2, are encoded by two genes with intronless coding regions. Human NAT1 protein is found in many tissues, unlike NAT2 which is present predominantly in the intestine and liver. We describe the exon-intron structure of the human NAT genes by analysing data from genomic databases. Comparison of expressed...

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PMID: 15853926
DOI: 10.1111/j.1742-7843.2005.pto_02.x

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Structural Analysis of the Genes for Human Arylamine N-Acetyltransferases and Characterisation of Alternative TranscriptsPMID 15853926Read ↗

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