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Article

Expression of arylamine N-acetyltransferases in pre-term placentas and in human pre-implantation embryos.

Human molecular genetics - 12 Apr 2000

Smelt V A, Upton A, Adjaye J, Payton M A, Boukouvala S, Johnson N, Mardon H J, Sim E

Abstract excerpt

Arylamine N -acetyltransferases (NATs) catalyse the acetylation from acetyl-CoA of arylamines and hydrazines. There are two human isoenzymes which show polymorphism, and both enzymes are involved in the activation and detoxification of environmental carcinogens and teratogens. The two human isoenzymes NAT1 and NAT2 show different tissue distribution, with human NAT2 being found in liver and intestine whilst human...

Topics

Acetylation
Arylamine N-Acetyltransferase
Blastocyst
Cytosol
DNA, Complementary
Gene Library
Genotype
Gestational Age
Humans
Isoenzymes
Oocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Placenta

Source

Identifiers

PMID: 10767335
DOI: 10.1093/hmg/9.7.1101

Genes

NAT1
NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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Expression of arylamine N-acetyltransferases in pre-term placentas and in human pre-implantation embryos.PMID 10767335Read ↗

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