Article
Ocular defects associated with a null mutation in the mouse arylamine N-acetyltransferase 2 gene.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Apr 2007
Wakefield Larissa, Long Hilary, Lack Nathan, Sim Edith
Abstract excerpt
The xenobiotic metabolizing enzyme, mouse arylamine N-acetyltransferase type 2 (Nat2), is expressed during embryogenesis from the blastocyst stage and in the developing neural tube and eye. Mouse Nat2 is widely believed to have an endogenous role distinct from xenobiotic metabolism, and polymorph...
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