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Tissue- and gender-specific expression of N-acetyltransferase 2 (Nat2*) during development of the outbred mouse strain CD-1.

Drug metabolism and disposition: the biological fate of chemicals - 1 Feb 2000

Estrada L, Kanelakis K C, Levy G N, Weber W W

Abstract excerpt

The human N-acetyltransferase (Nat2) genetic polymorphisms have been modeled in mouse strains. We determined the phenotype and genotype of the N-acetyltransferase 2 (Nat2*) gene among outbred CD-1 mice and found a mixed population of heterozygous and rapid and slow homozygous genotypes. Phenotypes determined with p-aminobenzoic acid demonstrated complete concordance of slow and rapid genotype and phenotype. The...

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PMID: 10640510

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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