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Article

pfcrt is more than the Plasmodium falciparum chloroquine resistance gene: a functional and evolutionary perspective.

Acta tropica - 1 Jun 2005

Cooper Roland A, Hartwig Carmony L, Ferdig Michael T

Abstract excerpt

Genetic, physiological and pharmacological studies are gradually revealing the molecular basis of chloroquine resistance (CQR) in the malaria parasite, Plasmodium falciparum. Recent highlights include the discovery of a key gene associated with resistance, pfcrt (Plasmodium falciparum chloroquine resistance transporter; PfCRT), encoding a novel transporter, and the characterization of global selective sweeps of...

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PMID: 15866507
DOI: 10.1016/j.actatropica.2005.04.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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