Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic and biochemical aspects of drug resistance in malaria parasites.

Current drug targets. Infectious disorders - 1 Mar 2004

Hayton K, Su X-z

Abstract excerpt

Drug resistance is one of the major factors contributing to the resurgence of malaria, especially resistance to the most affordable drugs such as chloroquine and Fansidar, a combination drug of pyrimethamine and sulfadoxine. Understanding the mechanisms of such resistance and developing new treatments, including new drugs, are urgently needed. Great progress has been made recently in studying the mechanisms of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chloroquine
Share to Dihydropteroate Synthase
Share to Malaria, Vivax

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mefloquine

Share to Phenanthrenes

Share to Plasmodium vivax

Share to Pyrimethamine

Share to Sulfadoxine

Source

Identifiers

PMID: 15032630
DOI: 10.2174/1568005043480925

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic and biochemical aspects of drug resistance in malaria parasites.PMID 15032630Read ↗

The mechanisms of resistance to antimalarial drugs in <i>Plasmodium falciparum</i>Semantic proximity Read ↗

Multiple drug resistance genes in malaria -- from epistasis to epidemiology.Semantic proximity Read ↗

Know your enemy: understanding the role of PfCRT in drug resistance could lead to new antimalarial tactics.Semantic proximity Read ↗

pfcrt is more than the Plasmodium falciparum chloroquine resistance gene: a functional and evolutionary perspective.Semantic proximity Read ↗

The genomic architecture of antimalarial drug resistanceSemantic proximity Read ↗

PfCRT and its role in antimalarial drug resistance.Semantic proximity Read ↗

A broad analysis of resistance development in the malaria parasite.Semantic proximity Read ↗

Molecular markers for drug resistance in malaria: use in treatment, diagnosis and epidemiologySemantic proximity Read ↗

Understanding drug resistance in malaria parasites: Basic science for public healthSemantic proximity Read ↗

Genomic Approaches to Drug Resistance in Malaria.Semantic proximity Read ↗

Profile of molecular mutations in pfdhfr, pfdhps, pfmdr1, and pfcrt genes of Plasmodium falciparum related to resistance to different anti-malarial drugs in the Bata District (Equatorial Guinea).Semantic proximity Read ↗

Sequence and gene expression of chloroquine resistance transporter (pfcrt) in the association of in vitro drugs resistance of Plasmodium falciparum.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.