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Article

Investigation of malaria susceptibility determinants in the IFNG/IL26/IL22 genomic region.

Genes and immunity - 1 Jun 2005

Koch O, Rockett K, Jallow M, Pinder M, Sisay-Joof F, Kwiatkowski D

Abstract excerpt

Interferon-gamma, encoded by IFNG, is a key immunological mediator that is believed to play both a protective and a pathological role in malaria. Here, we investigate the relationship between IFNG variation and susceptibility to malaria. We began by analysing West African and European haplotype structure and patterns of linkage disequilibrium across a 100 kb genomic region encompassing IFNG and its immediate...

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Source

Identifiers

PMID: 15858598
DOI: 10.1038/sj.gene.6364214

Genes

IFNG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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