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Article

Analysis of IL10 haplotypic associations with severe malaria.

Genes and immunity - 1 Sept 2005

Wilson J N, Rockett K, Jallow M, Pinder M, Sisay-Joof F, Newport M, Newton J, Kwiatkowski D

Abstract excerpt

We investigated the association between severe malaria and genetic variation of IL10 in Gambian children, as several lines of evidence indicate that IL10 is protective against severe malaria and that IL10 production is genetically determined. We began by identifying five informative SNPs in the Gambian population that were genotyped in a combined case-control and intrafamilial study including 654 cases of severe...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 15933743
DOI: 10.1038/sj.gene.6364227

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