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Article

Analysis of the cellular and molecular mechanisms of trophic action of a misspliced form of the type B cholecystokinin receptor present in colon and pancreatic cancer.

Cancer letters - 10 May 2005

Cheng Zhi-Jie, Harikumar Kaleeckal G, Ding Wei-Qun, Holicky Eileen L, Miller Laurence J

Abstract excerpt

Gastrin and cholecystokinin (CCK) have trophic action on cells expressing wild type A or B CCK receptors. Potential relevance to pancreatic and colonic cancers was raised by the demonstration of a misspliced type B CCK receptor that, when expressed in Balb3T3 cells, had constitutive activity to stimulate intracellular calcium. We attempted to confirm and extend this observation in CHO cells by establishing lines...

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Identifiers

PMID: 15837546
DOI: 10.1016/j.canlet.2004.09.008

Genes

CCK

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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