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Article

Molecular and functional characterization of the extracellular calcium-sensing receptor in human colon cancer cells.

Oncology research - 1 Jan 2003

Kállay Enikö, Bonner Elisabeth, Wrba Friedrich, Thakker Rajesh V, Peterlik Meinrad, Cross Heide S

Abstract excerpt

Presence of a functional extracellular calcium-sensing receptor (CaR) is of particular relevance for the growth-inhibitory action of Ca2+ on human colon carcinoma cells. In order to detect CaR gene alterations that may have occurred during the tumorigenic process, we applied Southern blot, DNA sequence, and RT-PCR analysis to DNA from normal human colon mucosa and from cancerous lesions of different grading, as...

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Identifiers

PMID: 12899245
DOI: 10.3727/000000003108748072

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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