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Article

SRC regulates constitutive internalization and rapid resensitization of a cholecystokinin 2 receptor splice variant.

The Journal of biological chemistry - 30 Sept 2005

Chao Celia, Ives Kirk L, Goluszko Elizabeth, Kolokoltsov Andrey A, Davey Robert A, Townsend Courtney M, Hellmich Mark R

Abstract excerpt

The third intracellular loop domain of G protein-coupled receptors regulates their desensitization, internalization, and resensitization. Colorectal and pancreatic cancers, but not the nonmalignant tissue, express a splice variant of the cholecystokinin 2 receptor (CCK2R) called CCK(2i4sv)R that,...

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Source

Identifiers

PMID: 16079138
DOI: 10.1074/jbc.M506337200

Genes

CCK
SRC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16079138-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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