Article
Internalization of the gastrin-releasing peptide receptor is mediated by both phospholipase C-dependent and -independent processes.
Molecular pharmacology - 1 Sept 1994
Benya R V, Akeson M, Mrozinski J, Jensen R T, Battey J F
Abstract excerpt
Consequent to agonist exposure, many G protein-coupled receptors undergo sequestration or internalization. Results with receptors linked to adenylate cyclase, such as the beta 2-adrenergic receptor, or receptors linked to phospholipase C (PLC) have provided conflicting results regarding the role...
Topics
- Alanine
- Amino Acid Sequence
- Animals
- Arginine
- Bombesin
- Cell Line
- Cricetinae
- DNA, Complementary
- Enzyme Activation
- Fibroblasts
- Gastrin-Releasing Peptide
- Glutamic Acid
- Glycine
- Humans
- Inositol Phosphates
- Mice
- Mice, Inbred BALB C
- Molecular Sequence Data